Perforin / APC / CB5.4
Perforin / APC / CB5.4
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-97512APC (View supplier product page) | |
| Size | 100 μl | |
| Price | $449.00 | |
| Antigen | Perforin | |
| Clone | CB5.4 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | APC | |
| Target Species | Mouse | |
| Applications | FC |
About Perforin and APC
| Perforin | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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