ATBF1 / DyLight 405 / 3B1
ATBF1 / DyLight 405 / 3B1
Product Details
Supplier | ||
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Catalog #: | H00000463-M01V (View supplier product page) | |
Size | 100 Tests | |
Price | $419.00 | |
Antigen | ATBF1 | |
Clone | 3B1 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | DyLight 405 | |
Target Species | Human | |
Applications | WB, IF, ICC | |
Description | IgG purified - - |
About ATBF1 and DyLight 405
ATBF1 | This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] | |
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DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |