ZAP70 / DyLight 350 / 1E7.2
ZAP70 / DyLight 350 / 1E7.2
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-50059UV (View supplier product page) | |
| Size | 100 μl | |
| Price | $349.00 | |
| Antigen | ZAP70 | |
| Clone | 1E7.2 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 350 | |
| Target Species | Human, Mouse | |
| Applications | WB, FC, ICC/IF |
About ZAP70 and DyLight 350
| ZAP70 | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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