FluoroFinder

	Supplier
	Catalog #:	H00007402-M01V2 (View supplier product page)
	Size	100 Tests
	Price	$419.00
	Antigen	Utrophin
	Clone	5G6
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	7C
	Target Species	Human
	Applications	WB, IF, ICC
	Description	IgG purified - -

	Utrophin	This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
	7C	7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry.

	Additional Sources

Utrophin / 7C / 5G6