ChT1 / DyLight 680 / RR5-89
ChT1 / DyLight 680 / RR5-89
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-65939FR (View supplier product page) | |
| Size | 100 μl | |
| Price | $379.00 | |
| Antigen | ChT1 | |
| Clone | RR5-89 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | DyLight 680 | |
| Target Species | Chicken | |
| Applications | FC |
About ChT1 and DyLight 680
| ChT1 | This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] | |
|---|---|---|
| DyLight 680 | DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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