WWP1 / DyLight 405 / 1A7
WWP1 / DyLight 405 / 1A7
Product Details
Supplier | ||
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Catalog #: | H00011059-M01V (View supplier product page) | |
Size | 100 Tests | |
Price | $419.00 | |
Antigen | WWP1 | |
Clone | 1A7 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | DyLight 405 | |
Target Species | Human, Primate | |
Applications | ICC, WB, IHC, IP | |
Description | IgG purified - - |
About WWP1 and DyLight 405
WWP1 | WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008] | |
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DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |