CD305 / DyLight 680 / 113
CD305 / DyLight 680 / 113
Product Details
Supplier | ||
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Catalog #: | NBP1-43784FR (View supplier product page) | |
Size | 100 Tests | |
Price | $359.00 | |
Antigen | CD305 | |
Clone | 113 | |
Host | Armenian Hamster | |
Isotype | IgG | |
Conjugate | DyLight 680 | |
Target Species | Mouse | |
Applications | FC | |
Description | Affinity purified |
About CD305 and DyLight 680
CD305 | The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] | |
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DyLight 680 | DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications. |