CD8a / DyLight 488 / 14550
CD8a / DyLight 488 / 14550
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-65930G (View supplier product page) | |
| Size | 100 Tests | |
| Price | $329.00 | |
| Antigen | CD8a | |
| Clone | 14550 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 488 | |
| Target Species | Chicken, Turkey | |
| Applications | FC, IP | |
| Description | Protein G purified |
About CD8a and DyLight 488
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
| Additional Sources |
|
|---|
