IL-13 / DyLight 488 / 13A
IL-13 / DyLight 488 / 13A
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-43723G (View supplier product page) | |
| Size | 100 Tests | |
| Price | $269.00 | |
| Antigen | IL-13 | |
| Clone | 13A | |
| Host | Rat | |
| Isotype | IgG1 κ | |
| Conjugate | DyLight 488 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Affinity purified - |
About IL-13 and DyLight 488
| IL-13 | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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