HDAC5 / DyLight 680 / 4G2
HDAC5 / DyLight 680 / 4G2
Product Details
Supplier | ||
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Catalog #: | H00010014-M01FR (View supplier product page) | |
Size | 100 Tests | |
Price | $419.00 | |
Antigen | HDAC5 | |
Clone | 4G2 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | DyLight 680 | |
Target Species | Human | |
Applications | ICC, WB | |
Description | IgG purified - - |
About HDAC5 and DyLight 680
HDAC5 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | |
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DyLight 680 | DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications. |