CD305 / DyLight 488 / lc12
CD305 / DyLight 488 / lc12
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-04317G (View supplier product page) | |
| Size | 100 μl | |
| Price | $399.00 | |
| Antigen | CD305 | |
| Clone | lc12 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 488 | |
| Target Species | Human | |
| Applications | WB, FC, ELISA |
About CD305 and DyLight 488
| CD305 | The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
| Additional Sources |
|
|---|
