FluoroFinder

	Supplier
	Catalog #:	H00006182-M01G (View supplier product page)
	Size	100 Tests
	Price	$419.00
	Antigen	MRPL12
	Clone	3B12-1A3
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	DyLight 488
	Target Species	Human
	Applications	IF, WB, IHC, ICC
	Description	IgG purified - -

	MRPL12	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008]
	DyLight 488	DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.

	Additional Sources

MRPL12 / DyLight 488 / 3B12-1A3