MTA-1 / PerCP / 4D11
MTA-1 / PerCP / 4D11
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00009112-M02PCP (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | MTA-1 | |
| Clone | 4D11 | |
| Host | Mouse | |
| Isotype | IgG3 κ | |
| Conjugate | PerCP | |
| Target Species | Human, Mouse, Rat | |
| Applications | WB, IF, ICC | |
| Description | IgG purified - |
About MTA-1 and PerCP
| MTA-1 | This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] | |
|---|---|---|
| PerCP | Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer. |
Citations
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