FluoroFinder

	Supplier
	Catalog #:	H00005688-M01G (View supplier product page)
	Size	100 Tests
	Price	$419.00
	Antigen	PSMA7
	Clone	1A10-3G12
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	DyLight 488
	Target Species	Human
	Applications	IF, WB, IHC, IP, ICC
	Description	IgG purified -

	PSMA7	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9. [provided by RefSeq, Jul 2012]
	DyLight 488	DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.

	Additional Sources

PSMA7 / DyLight 488 / 1A10-3G12