IL-21 R / DyLight 755 / 4A9
IL-21 R / DyLight 755 / 4A9
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-43356IR (View supplier product page) | |
| Size | 100 Tests | |
| Price | $299.00 | |
| Antigen | IL-21 R | |
| Clone | 4A9 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | DyLight 755 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Protein A or G purified |
About IL-21 R and DyLight 755
| IL-21 R | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] | |
|---|---|---|
| DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
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