DUSP4 / DyLight 755 / 1D12
DUSP4 / DyLight 755 / 1D12
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00001846-M08IR (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | DUSP4 | |
| Clone | 1D12 | |
| Host | Mouse | |
| Isotype | IgG3 κ | |
| Conjugate | DyLight 755 | |
| Target Species | Human | |
| Applications | ICC, WB | |
| Description | IgG purified - |
About DUSP4 and DyLight 755
| DUSP4 | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
| Additional Sources |
|
|---|
