PD-1 / DyLight 405 / AP-MAB0839
PD-1 / DyLight 405 / AP-MAB0839
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-06644V (View supplier product page) | |
| Size | 500 Tests | |
| Price | $459.00 | |
| Antigen | PD-1 | |
| Clone | AP-MAB0839 | |
| Host | Armenian Hamster | |
| Isotype | IgG2 | |
| Conjugate | DyLight 405 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Protein G purified |
About PD-1 and DyLight 405
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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