GAD65 / APC / 144
GAD65 / APC / 144
Product Details
Supplier | ||
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Catalog #: | NBP1-95043APC (View supplier product page) | |
Size | 100 Tests | |
Price | $519.00 | |
Antigen | GAD65 | |
Clone | 144 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | APC | |
Target Species | Human, Mouse, Rat | |
Applications | WB, FC, IP, RIA | |
Description | Affinity purified |
About GAD65 and APC
GAD65 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |