LXR beta / 7C / 1E1
LXR beta / 7C / 1E1
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00007376-M04V2 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | LXR beta | |
| Clone | 1E1 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | 7C | |
| Target Species | Human, Rat | |
| Applications | IF, WB, ICC | |
| Description | IgG purified - - |
About LXR beta and 7C
| LXR beta | The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010] | |
|---|---|---|
| 7C | 7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry. |
Citations
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