FluoroFinder

	Supplier
	Catalog #:	H00001021-M01APC (View supplier product page)
	Size	100 Tests
	Price	$419.00
	Antigen	Cdk6
	Clone	8H4
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	APC
	Target Species	Human, Rat
	Applications	WB, IHC, PLA, IF, ICC
	Description	IgG purified Proximity Ligation Assay - -

	Cdk6	The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

	Additional Sources

Cdk6 / APC / 8H4