IL-6 / PerCP / AP-MAB0848
IL-6 / PerCP / AP-MAB0848
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-06670PCP (View supplier product page) | |
| Size | 500 Tests | |
| Price | $459.00 | |
| Antigen | IL-6 | |
| Clone | AP-MAB0848 | |
| Host | Rat | |
| Isotype | IgG2 | |
| Conjugate | PerCP | |
| Target Species | Mouse | |
| Applications | FC, Block/Neutralize | |
| Description | Protein G purified |
About IL-6 and PerCP
| IL-6 | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| PerCP | Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer. |
Citations
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