NOD2 / 7C / 2D9
NOD2 / 7C / 2D9
Product Details
Supplier | ||
---|---|---|
Catalog #: | NB100-524V2 (View supplier product page) | |
Size | 100 Tests | |
Price | $329.00 | |
Antigen | NOD2 | |
Clone | 2D9 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | 7C | |
Target Species | Human, Mouse | |
Applications | WB, IHC, IP, IHC-P, ICC, IF | |
Description | Protein G purified |
About NOD2 and 7C
NOD2 | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014] | |
---|---|---|
7C | 7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry. |