FluoroFinder

	Supplier
	Catalog #:	H00000405-M01APC (View supplier product page)
	Size	100 Tests
	Price	$419.00
	Antigen	HIF-1 beta
	Clone	3D10
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	APC
	Target Species	Human
	Applications	ICC, WB, IHC
	Description	IgG purified - -

	HIF-1 beta	This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

	Additional Sources

HIF-1 beta / APC / 3D10