NBS1 / PE / 1D7
NBS1 / PE / 1D7
Product Details
Supplier | ||
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Catalog #: | NB100-221PE (View supplier product page) | |
Size | 100 μl | |
Price | $369.00 | |
Antigen | NBS1 | |
Clone | 1D7 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | PE | |
Target Species | Human, Mouse, Rat | |
Applications | WB, ICC/IF | |
Description | Protein G purified |
About NBS1 and PE
NBS1 | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |