CD124 / 7C / 49/20
CD124 / 7C / 49/20
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-65838V2 (View supplier product page) | |
| Size | 50 Tests | |
| Price | $309.00 | |
| Antigen | CD124 | |
| Clone | 49/20 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | 7C | |
| Target Species | Human | |
| Applications | WB, FC, IHC, ELISA, IHC-P | |
| Description | Protein A purified |
About CD124 and 7C
| CD124 | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012] | |
|---|---|---|
| 7C | 7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry. |
Citations
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