ATM / DyLight 350 / 2C1
ATM / DyLight 350 / 2C1
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-309UV (View supplier product page) | |
| Size | 100 μl | |
| Price | $429.00 | |
| Antigen | ATM | |
| Clone | 2C1 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 350 | |
| Target Species | Human, Monkey, Mouse, Rat | |
| Applications | WB, ELISA, IHC-P, ICC/IF, FC, IHC |
About ATM and DyLight 350
| ATM | The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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