FluoroFinder

	Supplier
	Catalog #:	H00000405-M01PCP (View supplier product page)
	Size	100 Tests
	Price	$419.00
	Antigen	HIF-1 beta
	Clone	3D10
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	PerCP
	Target Species	Human
	Applications	IF, WB, IHC, ICC
	Description	IgG purified - -

	HIF-1 beta	This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
	PerCP	Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer.

	Additional Sources

HIF-1 beta / PerCP / 3D10