ChT1 / DyLight 405 / RR5-89
ChT1 / DyLight 405 / RR5-89
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-65939V (View supplier product page) | |
| Size | 100 μl | |
| Price | $379.00 | |
| Antigen | ChT1 | |
| Clone | RR5-89 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | DyLight 405 | |
| Target Species | Chicken | |
| Applications | FC |
About ChT1 and DyLight 405
| ChT1 | This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] | |
|---|---|---|
| DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
| Additional Sources |
|
|---|
