IRF-4 / 7C / 2D1
IRF-4 / 7C / 2D1
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00003662-M05V2 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | IRF-4 | |
| Clone | 2D1 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | 7C | |
| Target Species | Human | |
| Applications | WB, IF, ICC | |
| Description | IgG purified - |
About IRF-4 and 7C
| IRF-4 | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010] | |
|---|---|---|
| 7C | 7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry. |
Citations
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