MRPL12 / DyLight 405 / 3B12-1A3

Product Details
Supplier
Catalog #: H00006182-M01V (View supplier product page)
Size 100 Tests
Price $419.00
Antigen MRPL12
Clone 3B12-1A3
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 405
Target Species Human
Applications WB, IHC, ICC
Description IgG purified - -
About MRPL12 and DyLight 405
MRPL12 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
DyLight 405 Excitation and Emission Spectra