SET / DyLight 405 / M1-F5
SET / DyLight 405 / M1-F5
Product Details
Supplier | ||
---|---|---|
Catalog #: | H00006418-M01V (View supplier product page) | |
Size | 100 Tests | |
Price | $419.00 | |
Antigen | SET | |
Clone | M1-F5 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | DyLight 405 | |
Target Species | Human | |
Applications | WB, IF, ICC | |
Description | IgG purified - - |
About SET and DyLight 405
SET | The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] | |
---|---|---|
DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |