FluoroFinder

	Supplier
	Catalog #:	H00023581-M01V (View supplier product page)
	Size	100 Tests
	Price	$419.00
	Antigen	Caspase 14
	Clone	4C9
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	DyLight 405
	Target Species	Human
	Applications	WB, ICC
	Description	IgG purified - -

	Caspase 14	This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
	DyLight 405	DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

Caspase 14 / DyLight 405 / 4C9