PKN1 / DyLight 350 / 1B10
PKN1 / DyLight 350 / 1B10
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00005585-M01UV (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | PKN1 | |
| Clone | 1B10 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | DyLight 350 | |
| Target Species | Human | |
| Applications | ICC, WB, IP | |
| Description | IgG purified - - |
About PKN1 and DyLight 350
| PKN1 | The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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