RUNX1T1 / DyLight 350 / 5A12
RUNX1T1 / DyLight 350 / 5A12
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00000862-M01UV (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | RUNX1T1 | |
| Clone | 5A12 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | DyLight 350 | |
| Target Species | Human | |
| Applications | WB, ICC | |
| Description | IgG purified - - |
About RUNX1T1 and DyLight 350
| RUNX1T1 | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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