KCNH1 / DyLight 488 / Polyclonal
KCNH1 / DyLight 488 / Polyclonal
Product Details
Supplier | ||
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Catalog #: | NBP1-42816G (View supplier product page) | |
Size | 100 μl | |
Price | $329.00 | |
Antigen | KCNH1 | |
Clone | Polyclonal | |
Host | Rabbit | |
Isotype | IgG | |
Conjugate | DyLight 488 | |
Target Species | Bovine, Human, Mouse, Rat | |
Applications | WB, ICC, IF | |
Description | Immunogen affinity purified |
About KCNH1 and DyLight 488
KCNH1 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] | |
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DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |