RB1 / DyLight 550 / OTI3F11
RB1 / DyLight 550 / OTI3F11
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-73821R (View supplier product page) | |
| Size | 100 μl | |
| Price | $529.00 | |
| Antigen | RB1 | |
| Clone | OTI3F11 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 550 | |
| Target Species | Human | |
| Applications | WB, IHC |
About RB1 and DyLight 550
| RB1 | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 550 | DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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