MGMT / DyLight 405 / OTI1B12

Product Details
Supplier
Catalog #: NBP2-72658V (View supplier product page)
Size 100 μl
Price $529.00
Antigen MGMT
Clone OTI1B12
Host Mouse
Isotype IgG1
Conjugate DyLight 405
Target Species Human
Applications WB, IHC
About MGMT and DyLight 405
MGMT Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Reviews & Ratings
DyLight 405 Excitation and Emission Spectra