CD4 Spark PLUS B574 (SK3, Mouse) - Reactivity: Human
Product Details
| Description | Spark PLUS B574 anti-human CD4 | |
|---|---|---|
| Conjugate | Spark PLUS B574 | |
| Clone | SK3 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | BioLegend | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About Spark PLUS B574
Spark PLUS B574™ from Biolegend is a fluorophore for use in both conventional and spectral flow cytometry with an excitation peak at 506 nm and an emission peak at 574 nm. While it’s suitable for both conventional and spectral flow, it demonstrates maximum brightness on spectral cytometers. It can be unmixed from colors like Spark PLUS B550™, FITC, and PerCP/Cyanine5.5, which makes it a good option for large spectral panels. It can be unmixed from PE on instruments with both blue and yellow/green lasers.
Spark PLUS B574™ from Biolegend is a fluorophore for use in both conventional and spectral flow cytometry with an excitation peak at 506 nm and an emission peak at 574 nm. While it’s suitable for both conventional and spectral flow, it demonstrates maximum brightness on spectral cytometers. It can be unmixed from colors like Spark PLUS B550™, FITC, and PerCP/Cyanine5.5, which makes it a good option for large spectral panels. It can be unmixed from PE on instruments with both blue and yellow/green lasers.
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