NECAB3 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb159960-100ug (View supplier product page)
Size 100 μg
Price $281.00
Antigen NECAB3
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications ELISA, WB, IHC-P, IF, ICC
Description Rabbit polyclonal antibody to APBA2BP.
About NECAB3 and Purified
NECAB3 The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Citations
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Purified Excitation and Emission Spectra