ErbB4 Polyclonal / Unconjugated /

Product Details
Supplier Abbexa
Catalog #: abx232829 (View supplier product page)
Size 100 μg
Price $462.00
Antigen ErbB4
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications ELISA, WB, IHC
Description ERBB4 Antibody is a Rabbit Polyclonal against ERBB4.
About ErbB4 and Purified
ErbB4 This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra