ChT1 Polyclonal / Unconjugated /

Product Details
Supplier Abbexa
Catalog #: abx231700 (View supplier product page)
Size 100 μg
Price $462.00
Antigen ChT1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications ELISA, WB, IHC
Description CHT1 Antibody is a Rabbit Polyclonal against CHT1.
About ChT1 and Purified
ChT1 This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
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Purified Excitation and Emission Spectra