BMPR-IB Polyclonal / Unconjugated /

Product Details
Supplier Abbexa
Catalog #: abx148133 (View supplier product page)
Size 100 μg
Price $245.00
Antigen BMPR-IB
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB, IHC
Description BMPR1B Antibody is a Rabbit Polyclonal against BMPR1B.
About BMPR-IB and Purified
BMPR-IB This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
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Purified Excitation and Emission Spectra