CD124 / APC / 209

Product Details
Supplier Sino Biological
Catalog #: 10402-R209-A (View supplier product page)
Size 100 Tests
Price $240.00
Antigen CD124
Clone 209
Host Rabbit
Isotype IgG
Conjugate APC
Target Species Human
Applications FC
Description This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-4R/CD124 (rh IL-4R/CD124; Catalog#10402-H08H; NP_000409.1; Met1-His232) and conjugated with APC under optimum conditions, the unreacted APC was removed.
About CD124 and APC
CD124 This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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APC Excitation and Emission Spectra