C7 / Unconjugated / 113

Product Details
Supplier Sino Biological
Catalog #: 13848-R113 (View supplier product page)
Size 100 μl
Price $199.00
Antigen C7
Clone 113
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications ELISA
Description This antibody was obtained from a rabbit immunized with purified, recombinant Human Complement component 7 (rh Complement component 7; Catalog#13848-H08H; P10643; Met1-Gln843).
About C7 and Purified
C7 This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016]
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Purified Excitation and Emission Spectra