CD111 / Unconjugated / 004

Product Details
Supplier Sino Biological
Catalog #: 80244-R004 (View supplier product page)
Size 100 μl
Price $199.00
Antigen CD111
Clone 004
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Rat
Applications ELISA
Description This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD111 / Nectin-1 / PVRL1 (Catalog#80244-R08H; XP_236210.3; Met1-Ala354).
About CD111 and Purified
CD111 This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
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Purified Excitation and Emission Spectra