ITCH / Unconjugated /

Product Details
Supplier Sino Biological
Catalog #: 11131-RP02 (View supplier product page)
Size 100 μl
Price $149.00
Antigen ITCH
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications ELISA
Description Produced in rabbits immunized with purified, recombinant Human ITCH / AIP4 (rh ITCH / AIP4; Catalog#11131-HNCE; NP_113671.3; Arg 526-Glu 903). ITCH / AIP4 specific IgG was purified by Human ITCH / AIP4 affinity chromatography.
About ITCH and Purified
ITCH This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
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Purified Excitation and Emission Spectra