IL-21 R / Unconjugated /

Product Details
Supplier Sino Biological
Catalog #: 11483-RP01 (View supplier product page)
Size 100 μl
Price $99.00
Antigen IL-21 R
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications ELISA
Description Produced in rabbits immunized with purified, recombinant Human IL-21R / Il21R (rh IL21R; Catalog#11483-H08H; Q9HBE5-1; Met1-Pro236). Total IgG was purified by Protein A affinity chromatography.
About IL-21 R and Purified
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
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Purified Excitation and Emission Spectra