FOXP2 / Unconjugated /

Product Details
Supplier Sino Biological
Catalog #: 102092-T34 (View supplier product page)
Size 100 μl
Price $149.00
Antigen FOXP2
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, ICC/IF, IF
Description Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human FOXP2, and purified by antigen affinity chromatography.
About FOXP2 and Purified
FOXP2 This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
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Purified Excitation and Emission Spectra