Bcl-6 / Unconjugated /

Product Details
Supplier Sino Biological
Catalog #: 12083-T16 (View supplier product page)
Size 100 μl
Price $149.00
Antigen Bcl-6
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications ELISA
Description Produced in rabbits immunized with purified, recombinant Human BCL6 (rh BCL6; Catalog#12083-H30E; P41182; Met1-Met150). BCL6 specific IgG was purified by Human BCL6 affinity chromatography.
About Bcl-6 and Purified
Bcl-6 The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra