APE1 / Unconjugated /

Product Details
Supplier Sino Biological
Catalog #: 103467-T46 (View supplier product page)
Size 100 μl
Price $149.00
Antigen APE1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Mouse
Applications WB, IHC-P, ICC/IF, IF, IP
Description Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Mouse APEX1/APE1/Ref-1, and purified by antigen affinity chromatography.
About APE1 and Purified
APE1 The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.[provided by RefSeq, Dec 2019]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra